More on ”Naevus Lentiginosus Linearis”: Reply

Do larger people have more naevi? Naevus frequency versus naevus density.

BACKGROUND It is unclear which of the number or the density of naevi on the skin is the more appropriate measure of risk of melanoma. Furthermore, the relationship between the number of naevi and their density in an individual has not been explored. Thus, for example, it is unknown if larger people tend to have more naevi by virtue of having a larger skin area, or if the density of naevi is sim...

Reply to more on: the role of thrombin in gliomas.

We thank Dr Arbit for his interest in our article. We have demonstrated that argatroban reduces peritumoral brain edema, tumor mass and improves tumor-induced neurological deficits in a rat glioma model [1,2]. As Dr Arbit suggests, argatroban may also be useful to reduce the deep vein thrombosis that can occur in glioma patients [3]. Argatroban is a small molecule that binds to the active site ...

Once More on Relative Truth a Reply to Skillen

Becker's naevus associated with connective tissue naevus.

Sir, Becker's naevus or Becker's melanosis is a relatively common disorder, which appears as a hyperpigmented, hypertrichotic patch located mainly on the trunk (1). Becker's naevus has been associated with various soft tissue and bony structural anomalies, such as hypoplasia of the ipsilateral breast, pectoralis major muscle, leg, arm and contralateral breast, spina bi®da, and pectus carinatum ...

Mucinous Naevus: A Rare Variant of Connective Tissue Naevus

Mucinous naevus (MN) is a type of benign hamartomatous cutaneous mucinoses characterized by deposition of excessive amounts of mucin in the superficial dermis in a diffuse pattern with absence of collagen and elastic fibres in the mucinous areas. It may be associated with features of connective tissue naevus of proteoglycan type [1]. There is paucity of literature regarding this interesting ent...